January 2008

UP FRONT
Editor's Page: Children Are Bearing the Brunt of Diabetes
By Thomas Moshang Jr, MD, and Steven M. Willi, MD

DIABETES THERAPY
The Pharmacology of GLP-1–Based Therapies
By Carolyn F. Deacon, PhD, DMSc, and Jens J. Holt, MD, PhD

PITUITARY, GONAD, AND ADRENAL CONDITIONS
Clinical Approach, Management of Acromegaly: An Update
By Laurence Katznelson, MD

THYROID DISORDERS
Replacement Therapy for Clinical Hypothyroidism
By Russell T. Joffe, MD

PEDIATRIC ENDOCRINOLOGY
Should Extremely Obese Adolescents Be Treated With Surgery?
By Holly M. Ippisch, MD, MS, and Thomas H. Inge, MD, PhD

WOMEN'S ENDOCRINOLOGY
Benefits and Risks of Hormonal Therapy in Postmenopause: An Update
By Anne Caufriez, MD, PhD

COVER STORY
Diabesity: Reversing an Epidemic
By Francine R. Kaufman, MD

Today's Pediatric Endocrinologists Must Also Be Health Care Advocates
By Jane L. Lynch, MD

The Tools They Are A-Changin'
By Gary Scheiner, MS, CDE

Racial Disparities Evident in Diabetes Mortality Among Children
Reviewed by Laura L. Polakowski, MD, MSPH

Two More Genetic Links to Type 1 Diabetes Uncovered
Reviewed by Joanna M.M. Howson, MD

Clinical Trial Updates: The Most Important Piece of the Puzzle in Curing Diabetes Is You

Treatment, Metabolic Control in Young Patients With Type 1 Diabetes
By Ina Knerr, MD; Peter Beyer, MD; Matthias Grabert, MS; Wolfgang Marg, MD; Birgit Rami, MD; Tilman Rohrer, MD; and Reinhard W. Holl, MD

DEPARTMENTS
Industry News and Innovations

Conference Calendar

5 Questions: Francine R. Kaufman, MD